Ischemic heart disease remains the leading cause of morbidity and mortality in the developed world. The high metabolism and oxygen demand of the cardiac myocardium rely on both increased blood flow and a rich capillary density. Therefore, the growth of the coronary vasculature is crucial, not only during early development but also for adults who face various physiological stresses.
This groundbreaking book explores the molecular mechanisms that govern the growth and assembly of coronary vessels. It provides a detailed examination of the hierarchy of the coronary vasculature, tracing its journey from embryonic origins through postnatal growth, adulthood, and even senescence. Key topics include:
- Normal coronary development
- Coronary anomalies and their underlying developmental errors
- Adaptations of coronary vessels to exercise training
- Impact of aging on coronary vasculature
- Responses to hypoxia and myocardial ischemia
- Cardiac hypertrophy and its effects on coronary function
This comprehensive overview of current research in coronary vessels and myocardial perfusion is authored by Dr. Robert J. Tomanek, Emeritus Professor of Anatomy and Cell Biology at the University of Iowa. Dr. Tomanek integrates findings from various fields of coronary vasculature research, making this book an invaluable resource for cardiovascular scientists and physicians.
Authors:
Robert J. Tomanek (Author)
Edition:
2013th
Publication Date:
October 19, 2012
From the book:
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