Unlock the Secrets of CNS Drug Discovery with Our Comprehensive Guide
This essential book focuses on central nervous system (CNS) drug discovery, providing invaluable insights into the intricacies of the blood-brain barrier (BBB). Designed for drug researchers and professionals in the pharmaceutical industry, it offers practical strategies for overcoming one of the most significant challenges in neurological drug development.
- Expert Insights: Authored by leading experts in the field, this book delivers practical solutions to enhance brain penetration and minimize CNS side effects, ensuring effective drug delivery.
- Comprehensive Tools Review: Explore state-of-the-art in silico, in vitro, and in vivo tools for assessing brain penetration and advanced CNS drug delivery techniques.
- In-Depth Coverage: Delve into BBB physiology, medicinal chemistry design principles, and the free drug hypothesis for the BBB, alongside transport mechanisms such as passive diffusion, uptake/efflux transporters, and receptor-mediated processes.
- Advanced Modelling Techniques: Learn about the latest advancements in modelling BBB pharmacokinetics and dynamics relationships (PK/PD)
Authors:
Li Di (Editor)
Edition:
1st
Publication Date:
February 2, 2015
From the book:
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