Gene and Cellular Immunotherapy for Cancer is an essential resource for anyone interested in the groundbreaking field of cancer treatment through advanced immunotherapy techniques. With the rapid growth and interest in clinical and preclinical exploration of gene and cellular immunotherapy, this book explores the development and approval of five Chimeric Antigen Receptor T-cell (CAR-T) products specifically for lymphoma and myeloma, along with one Bispecific T-Cell Engager (BiTE) for acute lymphoblastic leukemia (ALL). These revolutionary therapies have significantly transformed the management of patients suffering from relapsed refractory lymphoma, myeloma, and leukemia.
This comprehensive review covers the latest advancements in cellular and gene-based immunotherapies, making it an invaluable addition to the library of oncologists, immunologists, researchers, and clinical and basic science trainees. The book is structured into eighteen cohesive chapters that delve deeply into:
- Cellular-Based Immunotherapies: Detailed discussions on CAR-T, TCR-T, TIL, Viral CTLs, NK cells, and T/NK cell engagers.
- Historical Perspectives: Insight into the evolution of gene and cellular immunotherapy.
- Biology and Mechanisms: An exploration of the biological foundations that drive these innovative therapies.
- Development and Manufacturing: Comprehensive analysis of the processes involved in creating these therapies.
- Toxicities and Management: In-depth coverage of potential
Authors:
Armin Ghobadi (Editor)
Edition:
1st ed. 2022
Publication Date:
December 20, 2021
From the book:
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